Cryo-EM Scientist

University of Wisconsin

Madison, WI

Job posting number: #7237706

Posted: April 19, 2024

Application Deadline: Open Until Filled

Job Description

Job Summary:
The UW-Madison Cryo-EM Research Center (https://cryoem.wisc.edu) and the NIH-funded Midwest Center for Cryo-ET (https://www.cryoetportal.org) seek to hire a Cryo-EM Scientist to support the operations of our expanding cryo-electron microscopy (cryo-EM) and cryo-electron tomography (cryo-ET) facilities. The UW-Madison Cryo-EM Research Center and the NIH-funded Midwest Center for Cryo-ET are premier research facilities with missions to develop and to make available the advanced cryo-EM instrumentation and techniques for bioscience researchers from academia, government, or private industry laboratories. Instruments currently include two 300 kV Titan Krios TEMs, one 200 kV Talos Arctica TEM, one 120 kV Talos L120C TEM, two Aquilos 2+ cryo-FIB-SEMs, two Vitrobot plunge-freezers, Leica EM-GP2 plunge-freezer, CryoSol VitroJet, Leica Ice high-pressure freezer, Leica cryo-confocal CLEM system, cryo-ultramicrotome, Primo micropatterning system, optical microscopes, glow discharge, carbon-coating devices, and more.

As a team member, along with other center scientists, the Cryo-EM Scientist, will be responsible for training new center users; operations of the instruments on behalf of users; developing advanced analytical techniques on behalf of the centers; staying abreast of advances within the community in order to incorporate those techniques within the centers; and representing the centers within the broader community at meetings, conferences, exhibits, and through peer-reviewed publications. This position is an excellent opportunity for an individual to work with cutting-edge instrumentation for cryo-EM, cryo-ET, micro-ED, and cryo-FIB milling in state-of-the-art cryo-EM research facilities.

Ideally, we are looking for a colleague with previous EM, cryo-EM, light microscopy, or structural biology experience. However, there are ample opportunities for team training in all cryo-EM modalities. This Cryo-EM Scientist will join a team of scientists to support the growing cryo-EM research resources and community at UW-Madison.

Responsibilities:
Scientist I (RE043)
Scientist II (RE044)
Institutional Statement on Diversity:
Diversity is a source of strength, creativity, and innovation for UW-Madison. We value the contributions of each person and respect the profound ways their identity, culture, background, experience, status, abilities, and opinion enrich the university community. We commit ourselves to the pursuit of excellence in teaching, research, outreach, and diversity as inextricably linked goals.

The University of Wisconsin-Madison fulfills its public mission by creating a welcoming and inclusive community for people from every background - people who as students, faculty, and staff serve Wisconsin and the world.

For more information on diversity and inclusion on campus, please visit: Diversity and Inclusion

Education:
Required
Master's Degree in Biophysics, Chemistry, Biochemistry, Molecular Biology, Structural Biology, or related field.

Qualifications:
At least 3 years relevant research experience in the biological sciences that could include an understanding of cell biology, microbiology, protein biochemistry, or another appropriate sub-discipline. Preference for individuals with experience with light microscopy including fluorescence, electron microscopy, and/or cryo-electron microscopy. Experience with cryo-preparation techniques such as plunge-freezing, high-pressure freezing, cryo-microtomy, cryo-FIB milling, and other approaches is desired.




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