Summary

The Dhindsa Lab at Baylor College of Medicine invites applications for an open Research Technician II position. Our interdisciplinary team—composed of undergrads, grad students, and research staff—is focused on using innovative research approaches to advance research in neurodevelopmental and neurodegenerative diseases, including autism spectrum disorder, epilepsy, intellectual disability, and Parkinson’s Disease. We leverage human genetics, CRISPR-based technologies, and human iPSC-based models to uncover disease mechanisms and new therapeutic strategies. Our lab thrives on a culture of intellectual curiosity, collaboration, diversity, and a supportive environment. We are situated in the Neurological Research Institute, providing us with an outstanding network of collaborators and access to other cutting-edge technologies. Visit dhindsalab.com to discover more about our lab's culture and research.

The ideal candidate must be willing to work in a team, be organized, enjoy problem solving, and have strong communication skills. As you become familiar with our methodology, there will be opportunities to work independently on research projects. Based on your interest and expertise, you will be able to contribute to bioinformatics analysis of data as well. Past staff research associates have gone on to their top choice graduate school programs. 

Job Duties

• Develops and implements CRISPR/Cas9-based functional genomics approaches.
• Investigates the mechanisms of neurodevelopmental diseases and identify potential therapeutic strategies.
• Maintains stem cell cultures, including iPSCs and iPSC-derived neurons.
• Performs molecular biology techniques, such as constructing DNA vectors, western blots, and qPCR.
• Prepares samples for next-generation sequencing, conduct flow cytometry, and engage in biochemistry and functional assays.
• Carries out imaging and basic statistical calculations.
• Undertakes lab management tasks, not exceeding 25% of your time, such as preparing media, autoclaving, and managing inventories.

Minimum Qualifications

• Bachelor's degree in a Basic Science or related field. Four years of related experience may substitute for degree requirement.
• No experience required.

Preferred Qualifications

• One year of related work experience (relevant coursework may count toward this experience).
• Experience with neural cell culture (iPSCs) or other cell culture work with demonstrated proficiency in sterile technique
• Experience in molecular cloning techniques, quantitative PCR (qPCR), western blotting, and immunofluorescence.
• Working knowledge of flow cytometry and microscopy
• Bioinformatics experience, such as analysis of imaging or next-generation sequencing data
• Good Interpersonal, verbal, and communication skills.