Postdoctoral Fellow

University of Alabama at Birmingham

Birmingham, AL

Job posting number: #7085897

Posted: September 22, 2021

Application Deadline: Open Until Filled

Job Description

Postdoctoral Fellow – T-cell Leukemia (T-ALL), leukemic cell infiltration to the meninges, inflammation, and meningeal microenvironment
A postdoctoral position is available in the laboratory of Dr. Matlawska-Wasowska in the Department of Pharmacology and Toxicology, University of Alabama at Birmingham, USA (Dr. Matlawska is coming to UAB in January 2022) for a creative and highly motivated individual to work on a project associated with T-cell acute lymphoblastic leukemia (T-ALL) dissemination to the meninges. Ongoing research in the Matlawska’s laboratory focuses on the roles of inflammation and meningeal microenvironment on T-ALL colonization to the CNS/meninges. The lab utilizes several in vivo models of leukemia, patient derived xenografts, primary patient samples cell as well as various molecular biology approaches, genomics, metabolomics, biochemistry and high throughput screening.
This is an opportunity for a junior postdoctoral fellow with outstanding credentials in basic research of leukemia, immunology or cancer biology. The project will focus on discovering critical factors underlying T-ALL progression and infiltration of the CNS/meninges. This project will utilize multiparametric flow cytometry, distinct mouse models, human samples, imaging, RNAseq and scRNA sequencing.
The candidate must have expertise in immunology and leukemia biology, and must have experience in the generation and experimental use of mice (syngeneic, transgenic, PDX, humanized mice), multiparametric flow cytometry, cancer immunology and tissue culture models. Experience and/or interest in intravital imaging is desirable.
The candidate must have strong verbal and written communication skills, excellent computer skills; organizational and time management skills are also necessary. This position will enable the successful applicant to contribute to the development of high-impact research projects, to design and carry out experiments, to perform data analysis, to write manuscripts for publication and to write grant proposals. The successful candidate must be able to work in a team environment, pay close attention to detail and scientific rigor.

Ph.D. degree in cancer biology or immunology or neuroscience or related discipline.
Up to 1 year of postdoctoral experience.
Must have first author publications in peer-reviewed journals.

Additional Information:
When applying for the position, please include a cover letter with a statement of research interests and how they relate to this project, an updated CV and contact information for at least 3 references. The application should be sent to Salary and benefits are competitive and commensurate with research experience and background. They are based upon the NIH Ruth Kirschenstein Postdoctoral Fellow Scale.

About UAB: UAB is consistently rated among the top Universities according to U.S. News and World Reports. UAB is the No. 1 University in The Scientist’s “Best Places to Work for Postdocs”, with particular strengths in career development opportunities, training, and mentoring. UAB has also been named the Top Ranking Best Employer for New Graduates among institutions in education and No. 4 in the U.S. in general, and America’s No. 4 Best Employer for Diversity by Forbes. UAB has been named America’s No. 1 Best Large Employer by Forbes, topping the list of more than 500 public and private corporations, hospitals, universities, Fortune 500 companies and more, across dozens of industries.

UAB is an Equal Opportunity/Affirmative Action Employer committed to fostering a diverse, equitable and family-friendly environment in which all faculty and staff can excel and achieve work/life balance irrespective of, race, national origin, age, genetic or family medical history, gender, faith, gender identity and expression as well as sexual orientation. UAB also encourages applications from individuals with disabilities and veterans.

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