Research Fellow in Medicinal Chemistry

University of Leeds

Leeds, United Kingdom

Job posting number: #7080018 (Ref:EPSCH1037)

Posted: June 18, 2021

Job Description

Are you an ambitious researcher looking for your next challenge? Do you have an established background in medicinal chemistry, or a related discipline? Are you interested in antimicrobial resistance and developing novel antibacterial agents? Do you want to further your career in one of the UKs leading research intensive Universities?

Antibiotics are a cornerstone of modern medicine but they are under threat from antimicrobial resistance (AMR). We are looking for an ambitious, practical and enthusiastic scientist who can join a BBSRC-funded team in exploring novel binding pockets in bacterial DNA gyrase and topoisomerase IV to address AMR. Specifically, you will contribute to the molecular design and chemical synthesis of small molecules as inhibitors of bacterial topoisomerases. An extensive knowledge of organic synthesis and the ability to successfully synthesis biologically active molecules is essential.

You will hold  a   PhD  in  medicinal   chemistry, or  a closely allied discipline (or close to completion). You will be based in the  laboratory of Professor Colin Fishwick and Dr Martin McPhillie, in the School of Chemistry which has superb facilities for de novo molecular design and synthetic chemistry. You will also work closely with our collaborator Professor Tony Maxwell (John Innes Centre) and another funded Research Fellow performing the biochemistry and structural biology aspects. 


To explore the post further or for any queries you may have, please contact:

Professor Colin Fishwick, Professor of Medicinal Chemistry

Tel: +44 (0)113 343 6510 or email: C.W.G.Fishwick@leeds.ac.uk 


Please note: If you are not a British or Irish citizen, from 1 January 2021 you will require permission to work in the UK. This will normally be in the form of a visa but, if you are an EEA/Swiss citizen and resident in the UK before 31 December 2020, this may be your passport or status under the EU Settlement Scheme.


Location:  Leeds - Main Campus
Faculty/Service:  Faculty of Engineering & Physical Sciences
School/Institute:  School of Chemistry
Category:  Research
Grade:  Grade 7
Salary:  £33,797 to £40,322 p.a.
Due to funding restrictions an appointment will not be made above £36,914 p.a.
Working Time:  37.5 hours per week
Post Type:  Full Time
Contract Type:  Fixed Term (36 months (grant funding))
Release Date:  Wednesday 16 June 2021
Closing Date:  Sunday 18 July 2021
Interview Date:  To be confirmed
Reference:  EPSCH1037


The University community is made up of a wide range of people with diverse backgrounds and circumstances, which we value and regard as a great asset. As part of our continued commitment to equality and inclusion, we strive to create an environment where everyone can reach their full potential and have a real opportunity to participate in and contribute to our activities.


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