Research Assistant II Lab

Harvard Medical School

Boston, MA

Job posting number: #7079051

Posted: May 26, 2021

Application Deadline: Open Until Filled

Job Description

Job Summary

The successful candidate for this position will contribute to an interdisciplinary research team that is working to understand the genetic and cellular basis of normal human brain function and of brain disorders including Schizophrenia, Bipolar disorder and Huntington’s disease.

The McCarroll Lab (http://mccarrolllab.org) studies the human brain using a variety of approaches and technologies, many of which we invented in recent years and/or are further developing. These include approaches for analyzing RNA and proteins in thousands of individual cells simultaneously (https://www.youtube.com/watch?v=vL7ptq2Dcf0).

Our experiments involve high-throughput molecular profiling of the cells and nuclei sampled from human brain tissue, then analyzing the resulting data sets for insights about disease mechanisms and the ways in which genes and genetic variants act within the nervous system.

Coordination and collaboration within interdisciplinary research teams (that combine biology, statistics and data science) is a key aspect of this research.

Job-Specific Responsibilities

Characteristic responsibilities include:

• Contribute to experimental workflows for profiling the molecular contents and biological states of thousands of individual cells in brain tissue, contributing to all aspects including planning experiments; creating DNA-barcoding reagents; extracting nuclei from human brain tissue; preparing molecular libraries; and high-throughput DNA sequencing.

• Optimize and execute molecular-biological reactions such as PCR and high-throughput sequencing.

• Contribute to other projects as needed.

Basic Qualifications

College background or equivalent work experience, preferably in a related discipline. One or more year related work experience.

Additional Qualifications and Skills

Bachelor’s degree in biology, neuroscience, chemistry, biomedical engineering, or other quantitative area of science or engineering. Extensive course work could in some cases be equivalent to a major.

At least one year of laboratory experience.


Subjective qualifications:

Clear and effective in verbal and written communication

Able to critically read and discuss scientific research publications

Additional Information

This is a one-year term position with possibility of extension, contingent on work performance and continued funding to support the position.

Please note that we are currently conducting a majority of interviews and onboarding remotely and virtually. We appreciate your understanding.

We are committed to cultivating an inclusive workplace culture of faculty, staff, and students with diverse backgrounds, styles, abilities, and motivations. We appreciate and leverage the capabilities, insights, and ideas of all individuals. Harvard Medical School Mission and Community Values

Harvard University offers an outstanding benefits package including:
Time Off: 3 - 4 weeks paid vacation, paid holiday break, 12 paid sick days, 12.5 paid holidays, and 3 paid personal days per year.
Medical/Dental/Vision: We offer a variety of excellent medical plans, dental & vision plans, all coverage begins as of your start date.
Retirement: University-funded retirement plan with full vesting after 3 years of service.
Tuition Assistance Program: Competitive tuition assistance program, incredibly affordable classes directly at the Harvard Extension School, and discounted options through participating Harvard grad schools.
Transportation: Harvard offers a 50% discounted MBTA pass as well as additional options to assist employees in their daily commute.
Wellness options: Harvard offers programs and classes at little or no cost, including stress management, massages, nutrition, meditation, and complementary health services.
Harvard access to athletic facilities, libraries, campus events, and many discounts throughout metro Boston.
The Harvard Medical School is not able to provide visa sponsorship for this position.

Harvard Medical School strives to cultivate an environment that promotes inclusiveness and collaboration among students, faculty and staff and to create new avenues for discussion that will advance our shared mission to improve the health of people throughout the world.


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