Research Assistant I Lab

Harvard Medical School

Boston, MA

Job posting number: #7078792

Posted: May 20, 2021

Application Deadline: Open Until Filled

Job Description

Job-Specific Responsibilities

The Greenberg lab at Harvard Medical School examines how neuronal activity induced by sensory experience shapes the maturation and plasticity of the nervous system. Neuronal activity triggers a cascade of molecular signaling events in neurons, including modifications to the epigenome, transcriptome, and proteome, which promote long–lasting effects on the physiology and connectivity of neuronal networks. Our lab uses a combination of mouse genetics, biochemistry, and sequencing technologies to uncover new mechanisms controlling these signaling events and to explore their significance during development and in diseases of the nervous system. Specifically, we are seeking assistance for projects 1) exploring the role of neuronal activity in aging and nervous system rejuvenation and 2) examining the role of RNA stability in activity-dependent circuit plasticity. In this position, you will have the opportunity to learn cutting-edge molecular biology techniques, biochemical purification of protein complexes from tissue, new imaging modalities, mouse maintenance, and surgery, and in vivo screening of genetic elements controlling RNA turnover. You will also gain experience in bioinformatic analysis of sequencing and large-scale imaging datasets. We are looking to hire a curious, motivated, highly organized research assistant seeking experience in molecular neuroscience techniques. This position is ideally suited for individuals seeking to launch a career in research science or medicine.

Basic Qualifications

College background or equivalent work experience in a related discipline.

Additional Qualifications and Skills

Experience with working with mice preferred. Preference will be given to candidates that can commit for two years. Prior research experience is desirable, though not essential. At least one year related work experience (relevant course work may count towards experience).

Demonstrated abilities in basic laboratory techniques helpful, but not required. Exposure to applicable computer technologies, including specific software applications, may be required. Appropriate communications skills required. May be required to lift, move and transport related laboratory equipment. May be required to work with a variety of hazardous materials. While prior laboratory experience is helpful, most important is a candidate with curiosity, work ethic, organization, the ability to learn new techniques, and an excellent track record in college. We expect to teach the biochemical, molecular biology, and neuroscience approaches that will be used. This is an ideal position for a recent college graduate interested in preparing for graduate or medical school. Members from groups underrepresented in STEM are especially encouraged to apply.


Additional Information

This is a 12-month term appointment with the possibility of renewal contingent on funding.

Offer contingent upon successful completion of a pre-placement medical evaluation.


Harvard Medical School strives to cultivate an environment that promotes inclusiveness and collaboration among students, faculty and staff and to create new avenues for discussion that will advance our shared mission to improve the health of people throughout the world.


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