In Vivo Scientist (PDX focus)

The Jackson Laboratory for Genomic Medicine

Sacramento, CA

Job posting number: #7075958 (Ref:JAX28270)

Posted: March 12, 2021

Application Deadline: Open Until Filled

Job Description



The Product Development & Innovation In Vivo team at The Jackson Laboratory in Sacramento, CA has a new opportunity for a Ph.D. level  Scientist requiring experience and expertise in Patient Derived Xenografts (PDX), oncology and/or immuno-oncology research. Additional experience in in vivo pharmacology, flow cytometry and FACS experience is also highly desired. The ideal candidate has a proven track record of publications in these fields of expertise. It is desirable but not required that candidates have 1-5 years of experience in a contract research organization, biotechnology or pharmaceutical company. The individual will work

hands on at the research bench with murine PDX models for oncology and/or immuno-oncology. Managerial and project management experience are required. M.D. and M.S. candidates with equivalent experience will be considered.


What distinguishes the incumbent from each level is the level of supervision required, independent judgment used, complexity of projects, expertise in project coordination and negotiation, proficiency in problem solving, impact of errors, wider range of experience and specialized knowledge.


  • Works at the research bench on multiple PDX studies simultaneously. Provides regular updates regarding status of studies.
  • Leads a team of research technologists in supporting the department’s product lines.
  • Follows and supports all institutional policies, procedures and practices and ensures that staff is compliant.

  • Oversees technologist staff working on study and provides scientific and technical support as needed.

  • Supports and implements the development of new models for drug discovery in the areas of oncology and immunology.

  • Successfully launches commercial and/or research and development studies within timeframe agreed to in signed Statement of Work.

  • Accuracy of data entry, record keeping, maintenance of LIMS online system, and ensure all study activities are properly logged.

  • Year over year improvement in staff morale as measured by the yearly staff survey and higher staff retention levels.

  • Design and manage efficient and effective workflows.


  • Individuals with a Ph.D. (and/or M.D.) in oncology and/or immunology and a minimum of 2 years of experience as a postdoctoral fellow or in a contract research laboratory, pharmaceutical industry, or equivalent experience will be considered for the Scientist level. Applicants with less experience may be considered for an Associate Scientist position. Senior Scientists must have at least 2 years of industry experience at the Scientist level.  Individuals with a M.S. and a minimum of 8 years of basic research experience in oncology, immunology or pharmacology in a contract research laboratory, pharmaceutical industry, or equivalent experience will be considered.
  • Experience with in vivo PDX study design and animal research (preferably rodents) and animal welfare and regulatory guidelines.

  • Documented ability to develop and lead technical teams.
  • Strong leadership skills including a demonstrated ability to build key relationships, influence and motivate others.

  • Demonstrated success in making important decisions, often under some pressure and tight deadlines, which carry large financial consequences

  • Must have excellent human relation, communication and listening skills.
  • Excellent oral and written communication skills
  • Previous experience managing technical staff and project management are required.

About Us

The Jackson Laboratory (JAX, is a nonprofit biomedical research institute with over 2,000 employees whose mission is to discover precise genomic solutions for human disease and empower the global biomedical community in the shared quest to improve human health. A National Cancer Institute-designated Cancer Center, JAX has a mammalian genetics headquarters in Bar Harbor, Maine, a facility in Sacramento, California, and a genomic medicine facility, The Jackson Laboratory for Genomic Medicine (JAX-GM), in Farmington, Connecticut.


The JAX® Mice, Clinical and Research Services facility is located in Sacramento, the state capital of California.  Sacramento is less than a two-hour drive from San Francisco, Napa Valley, and scenic Lake Tahoe, and a short flight to both Los Angeles and Orange County.  Sacramento is the birthplace of the nation’s Farm to Fork movement, and offers excellent restaurants, gastro-pubs, wineries, theaters, and museums.  Outdoor activities are plentiful: Boating, white water rafting, and riding the scenic bicycle trails are popular.  Housing and other costs of living are more affordable in Sacramento and its surrounding suburbs than in most other neighboring areas in the North Bay, making Sacramento one of the hottest housing markets in the country year after year.




JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!




Our Values:


INTEGRITY - Courage and commitment to do what is right


PEOPLE - Inspiring our people to enhance the health of all


ONE TEAM - Unified by our promise to transform medicine and science


EXCELLENCE - Achieving world-class results


INNOVATION - Leading with discovery and creative solutions


STEWARDSHIP - Caring for and enhancing the resources entrusted to us




What do we have to offer?




JAX offers a dynamic and supportive work environment, competitive salaries and a comprehensive benefits package including a medical plan, outstanding retirement plan, generous paid time off and tuition reimbursement. 




Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.


Employment will require successful completion of references, background check, pre-employment physical, and drug test.


The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.




Learn more about at opportunities at JAX at

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More Info

Job posting number:#7075958 (Ref:JAX28270)
Application Deadline:Open Until Filled
Employer Location:The Jackson Laboratory for Genomic Medicine
United States
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