Senior/Principal Computational Scientist

The Jackson Laboratory for Genomic Medicine

Multiple Locations

Job posting number: #7074814 (Ref:JAX28338)

Posted: February 5, 2021

Application Deadline: Open Until Filled

Job Description


Computational Sciences, the central bioinformatics R&D department at The Jackson Laboratory, is seeking a Senior or Principal Computational Scientist who will participate in its collaborative bioinformatics program and make leading contributions to the cutting-edge projects in immunology and cancer immunology research at the interface of mammalian and human genetics at The Jackson Laboratory.


The successful candidate is expected to independently establish collaborations with the research and services groups working in immunology and cancer immunology at JAX and to provide leadership in grant applications as Co-I/multi-PI in the same. The other major areas of research at JAX include cancer biology, aging, immunology, metabolic disorders, neurobiology, and stem cell & developmental biology.   


The preferred location of this role is Farmington, CT. However, the role can also be located in Bar Harbor, CT. The option of working partially remote will be available upon further discussion.


  • Develop innovative computational approaches for immunology and cancer immunology studies, including integrative analysis of gene expression, proteomics, and physiological phenotypes
  • Interpretation of biological and/or translational relevance of analytical results obtained.
  • Participate and advise immuno-informatics strategic planning and developing the program in collaboration with respective faculty
  • Develop and deliver education on immuno-informatics for variety of audience
  • Coordinated, team-focused science involving multiple collaborators
  • Data presentation and visualization
  • Primary authorship of scientific publications and grant applications
  • Mentoring junior- and mid-level scientists
  • Presenting project strategies and results at relevant internal and external meetings


  • Minimum of seven (7) years of experience for Senior level and twelve (12) years of experience for Principal level in Bioinformatics research, excluding time spent to obtain PhD. Candidates with significant pre-doctoral experience in the relevant research area as a researcher and demonstrated research track record during the pre-doctoral period will also be considered.
  • Demonstrated experience managing complex projects and collaborations as indicated by collaborative and lead author publications.
  • Demonstrated ability to develop and deliver bioinformatics software, especially relevant to immunology and cancer immunology.
  • Demonstrated experience in conducting education in bioinformatics and/or Immuno-informatics.
  • An in-depth understanding of immunology and immuno-informatics
  • Experience working immunology and cancer immunology data analysis
  • Experience with “omics” data analysis, machine learning & biostatistics preferred

About Us

Computational Sciences at The Jackson Laboratory

Computational Sciences is a central department that runs a fully integrated comprehensive collaborative program in bioinformatics and computational biology in all major areas of research and development at The Jackson Laboratory. Our focus is to adopt and innovate-in emerging technological opportunities and make leading contributions to the scientific programs at The Jackson Laboratory. The program is delivered by an agile group of 50+ highly dynamic and experienced Computational Scientists and software engineers whose team-focused scientific work is supported by well-established project management and collaboration with IT. The staff of Computational Sciences co-authored 130+ papers in 5year span, including reviews and book chapters, in a wide variety of areas of bio-medical and computational research; participate as primary authors in 15+ grant applications/year; delivered numerous talks at international meetings; co-leading the informatics components of number of research programs such as Mouse Phenome Database, Genetic Diversity Initiative, Center for Systems Neurogenetics of Addiction, Single Cell Genomics, and Patient Derived Xenografts.



The Jackson Laboratory (JAX) is an independent, nonprofit biomedical research institution with more than 2,300 employees. Headquartered in Bar Harbor, Maine, it has a National Cancer Institute-designated Cancer Center in Augusta, Maine, a genomic medicine institute in Farmington, Connecticut, and facilities in Ellsworth, Maine, Sacramento, California, and Shanghai, China. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.


JAX Genomic Medicine is transforming medicine by improving patient care, lowering costs, and increasing life span and health span. JAX Genomic Medicine’s research focuses on the complex genetic causes of disease and on the development of genomic solutions tailored to each person's unique genetic makeup.


JAX Genomic Medicine sits on a 17-acre site on the campus of the University of Connecticut Health Center. The 183,500-square-foot facility opened in the fall of 2014. Now, it houses over 300 biomedical researchers, technicians, and support staff in state-of-the-art computing facilities and laboratories.


In Connecticut, JAX resides in the scenic town of Farmington, in the state’s capitol region. The Hartford region, which offers some of the best public schools in the country, is made up of both bigger cities and smaller, charming historic New England towns.  JAX Genomic Medicine is also geographically located within 2 hours of Boston and New York and is close to multiple transportation systems, including bus lines, highways, railroads and international airports.


JAX employees work in a collaborative, value-driven, and team-based environment where the focus is on advancing science and improving patients’ lives. Researchers apply genetics to increase the understanding of human disease and advance treatments and cures for cancer, neurological and immune disorders, diabetes, aging, and heart disease. JAX was voted among the top 15 “Best Places to Work in Academia” in the United States in a poll conducted by The Scientist magazine!


Our Values:

INTEGRITY - Courage and commitment to do what is right

PEOPLE - Inspiring our people to enhance the health of all

ONE TEAM - Unified by our promise to transform medicine and science

EXCELLENCE - Achieving world-class results

INNOVATION - Leading with discovery and creative solutions

STEWARDSHIP - Caring for and enhancing the resources entrusted to us


What do we have to offer?

JAX offers a dynamic and supportive work environment, competitive salaries, and a comprehensive benefits package, including a medical plan, outstanding retirement plan, generous paid time off, and tuition reimbursement including an MBA program. Our campus offers a fitness center with an award-winning wellness program and an onsite full service cafeteria.


Most importantly, every position contributes to JAX’s mission of discovering precise genomic solutions for human disease and empowering the global biomedical community in our shared quest to improve human health.


Employment will require successful completion of references, background check, credit check, and an appropriate non-compete agreement.

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.

Learn more about career opportunities at JAX:


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More Info

Job posting number:#7074814 (Ref:JAX28338)
Application Deadline:Open Until Filled
Employer Location:The Jackson Laboratory for Genomic Medicine
United States
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