The purpose of this Bioinformatics Analyst II position is to support the Clinical Genome Resource (Clingen) (https://clinicalgenome.org/), an NIH-funded effort dedicated to developing resources for defining the clinical relevance of genes and variants for use in precision medicine and research. Resources that will be supported by this position include the ClinGen Allele Registry the ClinGen Actionability Curation Interface and the ClinGen Evidence Repository. The Bioinformatics Analyst II will play a key role in evaluating requirements and performing feasibility studies for current resources, and developing new applications. The Bioinformatics Analyst II will support projects by implementing improvements to existing Clingen resources, identifying and integrating Clingen repositories, evaluating requirements for conducting new types of analyses, developing user interfaces to effectively present clinical data and supporting information, soliciting user feedback, and implementing and testing solutions in close collaboration with consortium members.
Review and evaluate current Clingen pipelines and prioritize improvements with Clingen collaborators and stakeholders.
Ensure that Clingen genetic variation tools and pipelines are developed, tested, run, and delivered on time.
Work with BRL software development team to design, code, implement, test, and debug Clingen programs and tools, and manage timelines.
Prepare program documentation and educate users on the new functionalities.
Develop use cases to guide user adoption.
Participate in the integration of high-volume data sets.
Design, implement, and execute Clingen resources; and work with BRL staff to integrate new tools for genetic data analysis and visualization.
Bachelor's degree in Genetics, Biology, Bioinformatics, Biostatistics, Computational Biology, Computer Science, or a related field.
One years of relevant experience.
Master’s degree in a related field.
Candidates must have a solid understanding and experience in programming, preferably in scripting languages. The successful candidate will be able to design, code, test, and debug generic software solutions with an emphasis on reusability, and which extend an existing system. Successful applicants will present and discuss requirements, specifications, backend and UI designs, create necessary test data, test software, and prepare documentation.
In addition, candidates must have excellent English-language communication skills, interpersonal skills, and be capable of working within a team of biologists and programmers. Candidates who can contribute to system administration of in-house virtualized and non-virtualized IT assets as a minor duty will also be viewed favorably.
A working understanding of mutexes, threads, guards, and conditional and atomic variables.
An ability to contribute to and use shared object-oriented code libraries.
Functional familiarity with one or more modern 3rd generation languages such as Python, Ruby, Perl, and/or EcmaScript 5/6, as well as standard web technologies such as Ajax, CSS, HTML, REST APIs, JSON-LD. Typical data processing pipelines will operate in a GNU/Linux environment and be implemented using programming languages such as Python, Ruby, and NodeJS.
Experience with document, graph, and relational databases is a plus.
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Baylor College of Medicine is an Equal Opportunity/Affirmative Action/Equal Access Employer.
Baylor College of Medicine fosters diversity among its students, trainees, faculty and staff as a prerequisite to accomplishing our institutional mission, and setting standards for excellence in training healthcare providers and biomedical scientists, promoting scientific innovation, and providing patient-centered care.
- Diversity, respect, and inclusiveness create an environment that is conducive to academic excellence, and strengthens our institution by increasing talent, encouraging creativity, and ensuring a broader perspective.
- Diversity helps position Baylor to reduce disparities in health and healthcare access and to better address the needs of the community we serve.
- Baylor is committed to recruiting and retaining outstanding students, trainees, faculty and staff from diverse backgrounds by providing a welcoming, supportive learning environment for all members of the Baylor community.