Postdoctoral Fellow - Metabolic Mechanisms Leading to Obesity, Diabetes, and Cancer

City of Hope

Duarte, CA

Job posting number: #7071817 (Ref:10008317)

Posted: November 5, 2020

Application Deadline: Open Until Filled

Job Description

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer, diabetes and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

City of Hope has one of the most influential diabetes research programs in the world. Our scientists’ work has revolutionized the understanding and treatment of the disease and continues today with exciting developments in cell transplantation, gene regulation, immune tolerance and gaining systemic understanding of diabetes as a complex, multifaceted disease.

To learn more about our exciting research and accomplishments in the field of Diabetes, please visit https://www.cityofhope.org/research/diabetes-metabolism-research-institute

Position Summary

NIH-funded postdoctoral research position is available in the laboratory of Qiong (Annabel) Wang, in the Department of Molecular and Cellular Endocrinology at the City of Hope Beckman Research Institute.

The Wang laboratory studies the function and remodeling of fat tissue, both in physiological and pathological conditions, such as insulin resistance, obesity, and cancer.

Work in the lab utilizes the cutting-edge tissue-specific, inducible knockout and labeling mouse models (Nature Medicine, 2013; Nature Cell Biology, 2015). Besides in vivo metabolic phenotyping and lineage tracing, our lab routinely performs single-cell sequencing, 3D tissue imaging, as well as new assay development. The Wang lab is currently focusing on three areas: 1) Brown fat cell heterogeneity, and how this heterogeneity remodels the thermogenic capacity of brown adipocytes in health and disease (Journal of Clinical Investigation, 2020). 2) adipocyte remodeling in the mammary gland, and adipocyte-epithelium cross talk in health, metabolic disorders, and breast cancer (Cell Metabolism, 2018). 3) Aging-associated adiposity and metabolic disorders.

Complete List of Publications:
https://www.ncbi.nlm.nih.gov/myncbi/qiong.wang.1/bibliography/public/

We are seeking an independent and highly motivated candidate interested in studying the molecular, cellular, and metabolic mechanisms leading to obesity, diabetes, and cancer. Preferably with expertise in using mouse models to study metabolic diseases.

Qualifications
Basic education, experience and skills required for consideration:
Ph.D. and/or M.D. degree in life or biomedical sciences, or a related discipline is required.
Extensive experience in basic molecular biology skills.
Experience in animal models.
Experience in immunofluorescence staining and flow cytometry, or scRNA-seq analysis.
Excellent written and verbal communication skills.
Good problem-solving skills, ability to conduct independent research, ability to work effectively in a team.

Additional Information:
About Dr. Wang: Qiong (Annabel) Wang, PhD Qiong Wang, Ph.D., joined the Diabetes & Metabolism Research Institute at City of Hope as an Assistant Professor in the Department of Molecular and Cellular Endocrinology .

For more information about the Wang Lab, please click here .

To apply: please include an updated CV and a list of three professional references.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.
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City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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