Postdoctoral Fellow - Cancer Genetics and Epigenetics

City of Hope

Duarte, CA

Job posting number: #7068594 (Ref:10006624)

Posted: August 6, 2020

Application Deadline: Open Until Filled

Job Description

Thank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions.

About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
Postdoctoral positions are now available in the laboratory of Dr. Yilun Liu at the Department of Cancer Genetics and Epigenetics, Beckman Research Institute of City of Hope. Dr. Liu’s research focus relates to (1) dissecting the mechanism by which cells prevent the formation of endogenous DNA breaks as a consequence of unresolved collision between a replication fork and a transcription machinery or a transcription-induced R-loop; (2) developing pharmaceutical mechanisms for cancer therapy by targeting enzymes important for resolving R-loops or transcription-replication collisions to enhance DNA break formation as well as factors important for the BRCA2 and PARP-dependent repair pathways to keep these DNA breaks unrepaired; and (3) targeting mitochondrial DNA as signaling molecule in immune response and cancer therapy.

Qualifications
Basic education, experience and skills required for consideration:
  • A Ph.D. degree in life or biomedical sciences, or a related discipline is required.
  • Experience in biochemistry and/or cell biology is preferred
Additional Information:
  • For more information on Dr. Yilun Liu’s research please visit, here .
  • Dr. Liu’s group has published in journals, including Nature Communications, Cell Reports, EMBO Journal and PNAS. A full list of publications can be found here .
  • Please submit curriculum vitae electronically to yiliu@coh.org .
City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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City of Hope is a community of people characterized by our diversity of thought, background and approach, but tied together by our commitment to care for and cure those with cancer and other life-threatening diseases. The innovation that our diversity produces in the areas of research, treatment, philanthropy and education has made us national leaders in this fight. Our unique and diverse workforce provides us the ability to understand our patients' needs, deliver compassionate care and continue the quest for a cure for life-threatening diseases. At City of Hope, diversity and inclusion is a core value at the heart of our mission. We strive to create an inclusive workplace environment that engages all of our employees and provides them with opportunities to develop and grow, both personally and professionally. Each day brings an opportunity to strengthen our work, leverage our different perspectives and improve our patients’ experiences by learning from others. Diversity and inclusion is about much more than policies and campaigns. It is an integral part of who we are as an institution, how we operate and how we see our future.


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More Info

Job posting number:#7068594 (Ref:10006624)
Application Deadline:Open Until Filled
Employer Location:City of Hope
Duarte,California
United States
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