Research Associate

University of Virginia

Charlottesville, VA

Job posting number: #7062564 (Ref:R0012254-1)

Posted: December 3, 2019

Application Deadline: Open Until Filled

Job Description

The Bushweller Laboratory in the Department of Molecular Physiology and Biological Physics at the University of Virginia seeks a Research Associate. The successful candidate will perform research in medicinal chemistry focused on developing small molecule inhibitors of transcription factors that are drivers of cancer. The primary focus will be on the development of small molecule inhibitors targeting the AML1-ETO transcription factor driver in leukemia which we have published on. The project requires skills and expertise in synthetic chemistry, compound characterization, and modeling. The project also requires the ability to work effectively with others carrying out cellular and animal studies of the inhibitors to advance the project.

More information about the lab can be found on our website:

The initial job duties for this person will be planning and carrying out the synthesis of new inhibitors of AML1-ETO and collaborating with others to characterize their effects in cells and in animals. It is expected that all compounds will be thoroughly characterized prior to biological testing. This person will also be responsible for training graduate and undergraduate students.

The highly motivated candidate must have a Ph.D. in Chemistry, Medicinal Chemistry, or Chemical Biology, or a related field and must have at least two publications in peer-reviewed journals, extensive experience in chemical synthesis and compound purification and characterization. The ability to work independently yet to interact well with a diverse group of scientists and students is essential.

To apply for this position, please use the link below:

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